Nicholas Frankel

Company: Senti Biosciences Inc.

Job title: Associate Director-Gene Circuit Discovery

Seminars:

Prolonging Persistence & Enhancing Safety Through Inducible & Armoring Strategies 9:30 am

Investigating the role of inducible promoters and synthetic circuits in regulating CAR-T cell activation and persistence Exploring various armoring strategies to protect CAR-T cells from the immunosuppressive tumor microenvironment and enhance their therapeutic efficacy Discussing the combination of inducible and armoring approaches to create highly potent and safe CAR-T cell therapiesRead more

day: Conference Day Two

Expert Discussion – Translating Inducible & Logic-Gated Cell Therapies to the Clinic 10:00 am

Addressing the challenges and opportunities associated with translating inducible cell therapies to clinical application Discussing the development of appropriate clinical trial designs and endpoints to evaluate the safety and efficacy of these advanced cell therapies Exploring the potential of patient-specific factors and biomarkers to optimize the selection and treatment of patients with inducible and logic-gated…Read more

day: Conference Day Two